It is also important to underline the fact that thirty-eight out of the 365 concepts are 'not definable' (nd) indicating that these concepts express rather general and unspecific concepts (e.g. "I am well informed about hemophilia" (Haemo-QoL)).
The works cited in our discussion make reference to other pain management strategies, unimodal approaches, or rather unspecific pain therapy concepts.
Alongside this relatively unspecific explication of the concept of EB, the discussion so far also lacks an analysis of the practical problems that threaten to arise on any non-trivial determination of what evidence-based ethics might mean.
Forty-four concepts were labelled not definable, which means that the concept is too unspecific to be assigned to a concrete ICF category (for example, quality of life in general).
Due to its very character as a framework many of IRC/IAD and MS concepts remain comparatively general and unspecific, making it somewhat difficult for practitioners to apply and operationalize them.
In order to analyze if this concept can also be applied on unspecific AOS, we generated a PpAOS1 variant with the respective Phe to Leu-substitution and analyzed the products formed by incubating purified protein with different 9- and 13-hydroperoxy C18-fatty acids as substrate.
The vigilance concept we refer to in our study describes unspecific activation states of the central nervous system on the sleep-wake spectrum as they are empirically assessable by EEG.
The concept of inefficiency could be further refined by distinguishing the case where there is unspecific increased neural activity versus the case where there is a specific increase in activity due to the maintenance of incorrectly encoded material.
For the fold change, we map (5) and compute membership values for both categories via the weighting functions (displayed in Fig. 2b), resulting in a pair (6) Analogously, we map, using Figure 2a, to areas of low and high significance in the fuzzy concept (7) For both measures, a third category can optionally be introduced to account for unspecific signals in case of very noisy data.
All these concepts postulate an "accelerated aging" phenotype of RBCs during malaria that leads to clearance of RBCs by unspecific mechanisms.
