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It is therefore conceivable that changes of latencies can be regarded as a signature of global, regionally unspecific age-related changes.
Most of the discussed markers for PD seem to be unspecific with older age, but related to SN+.
The 10-item NDI was translated into German and administered to 558 patients with chronic unspecific neck pain (Mean age 49.9 ± 11.4 years, 76% female).
CPK was normal and muscle biopsy at 2 years of age only showed unspecific myopathic changes.
Since our model uses throughout gender unspecific input-data, we calculated age-specific average values from both gender (Table 2).
However, MTA is unspecific and occurs in normal ageing as well as in small vessel disease without cognitive impairment.
These data suggest that neonates, even at 37 weeks of gestational age, tend to show unspecific elevation of serum levels of 17-OHP by cross-reaction for adrenal steroids from fetal adrenal cortex (Fig. 2).
Importantly, no LacZ+ keratinocytes were observed after 6 months of tracing in control litter mates treated with oil, thereby excluding unspecific activation of Cre enzyme in aging skin.
Finally, the described neurophysiological changes may be related to an unspecific decrease of overall cortical excitability with age.
No evaluation has been made on the climbing fibre varicosity distribution since at this age the VGlut2 marker is unspecific [43].
Interestingly, even early studies from the seventies and eighties concluded that gross lesions seem similar and unspecific irrespective of the underlying aetiology in this age group of piglets [ 16, 17].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com