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Features of classic tyrosinemia include severe liver disease, unsatisfactory weight gain, peripheral nerve disease, and kidney defects.
Defective membrane transport of lysine, arginine, and ornithine in the intestines causes lysinuric protein intolerance (LPI), a disorder characterized by protein intolerance, diarrhea, unsatisfactory weight gain, osteoporosis, and rashes; late complications of LPI include kidney and lung disease.
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Unfortunately, the application of PediaSat to our small cohort of patients below 10 kg of body weight provided unsatisfactory results: the PediaSat catheter provided unacceptable saturation differences, with respect to the reference ScvO2 values (-26 to 25%).
For the inner atoms, CB, CG and CD1 of TYR 225, and CB of LYS 258, the separations are unsatisfactory, resulting in small weights that are nearly zero.
One animal in the last group to be sacrificed was euthanized after 8 weeks, as its weight gain was unsatisfactory.
In the absence of any theoretical or empirical guidance, we regard our weighting scheme as the least unsatisfactory of the readily available alternatives.
The effect of metformin on weight reduction in polycystic ovary syndrome (PCOS) is often unsatisfactory.
However, its effect on weight reduction as an adjuvant to lifestyle modification is often unsatisfactory (6, 7).
We would contend that weight loss without clear proof-of-mechanism would be an unsatisfactory, although clearly not untenable, position for a centrally acting agent.
Inadequate demographic information (e.g., patient's name, weight or age at the time of collection) also may render a specimen unsatisfactory.
Thus, simple linear combination with fixed weights between the spatial saliency map and the temporal saliency map may lead to unsatisfactory result.
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