Exact(2)
However, these reported biosensors were witnessed by the narrow linear range, low sensitivity and unsatisfactory stability.
Peptidomimetic aldehydes can show high selectivity in biochemical assays; however, the chemical reactivity of aldehydes, leading to reversible Schiff base formation with proteins, metabolic oxidation and reduction, and pH-dependent hydrate formation, result in unsatisfactory stability and bioavailability, underlying a lack of progress to the clinic.
Similar(56)
Unfortunately, most of them suffer from one or more problems like high cost, complicated preparative process, limited specific capacitance, unsatisfactory cycling stability, and low rate capability.
Iron oxides are considered as attractive electrode materials because of their capability of lithium storage, but their poor conductivity and large volume expansion lead to unsatisfactory cycling stability.
However, the SUV methodology has well-known shortcomings such as uptake time dependence of the SUV, unsatisfactory test/retest stability, susceptibility to errors in scanner calibration etc. [1 6] all of which adversely affect the reliability of the SUV as a surrogate of the metabolic rate of FDG (and ultimately of glucose consumption).
The pentagon fraction obtained from a Voronoi polygon analysis and atomic displacement during plastic deformation directly computed using the atomistic approach can be selected as quantities that have an acceptable correlation with plasticity, even though the clearness and the statistical stability are unsatisfactory.
As promising cathode materials in Li-ion batteries, Li-rich layered oxides still suffer from unsatisfactory rate capability and cyclic stability during cycling.
After the hit compound had been obtained, our modifications successfully increased TAK1 inhibitory activity and solubility, but metabolic stability was still unsatisfactory.
But unpredictable stability, high price and unsatisfactory life hold back their industrializations.
However, the pharmacokinetics and metabolic stability of the tracers was unsatisfactory for potential clinical application.
"Viewed through the lens of the Federal Reserve's dual mandate — the pursuit of the highest level of employment consistent with price stability — the current situation is wholly unsatisfactory," the New York Fed president, William C. Dudley, said in a speech in Midtown Manhattan.
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