Autism Diagnostic Observation Schedule (Lord et al., 2000) module 4 was performed but the score was not used as an inclusion criterion due to its potentially unsatisfactory sensitivity to high-functioning adults with autism, particularly females (Lai et al., 2011).
The early diagnosis has two main obstacles: 1) the early changes in the tissue's fine structure and delicate functions markedly precede the development of OA as a clinical disease; and 2) current diagnostic imaging has insufficient resolution and unsatisfactory sensitivity to detect early (i.e., small) lesions in cartilage.
3) LPAs are relatively specific but unsatisfactory sensitivity affects the molecular tests for resistance to quinolones and, even more so, to SLIDs.
In this context, the third edition of the ACCP guidelines on the diagnosis and management of lung cancer stated that nonsurgical biopsy should not be used to exclude malignancy considering its unsatisfactory sensitivity and limited negative predictive value [ 3].
Despite the recent and debatable input of fluorodeoxyglucose positron emission tomography [ 27, 28] to standard work-up with morphological examination with biopsies, cCR remains difficult to assess accurately, because of the unsatisfactory sensitivity of CT and EUS, in the restaging after CRT [ 13, 14].
Baseline CVP was an adequate predictor of %DCI (AUC = 0.68, 95% confidence interval = 0.54 to 0.83; P = 0.01), but with an unsatisfactory sensitivity and specificity (67%and54%4%, respectively).
Techniques such as elastic recoil detection analysis show unsatisfactory sensitivity since it works with the samples placed into a high vacuum chamber[10].
Previous studies in this field have reported the usefulness of stool DNA testing in experimental settings but only modest or unsatisfactory sensitivity for cancer and advanced adenoma were observed in population-based study [ 40].
This combination of cytology and PAX1 m testing improved the unsatisfactory sensitivity of using cytology alone, without greatly compromising its specificity and is more suitable in developed countries where the cytology infrastructure has reached its limits.
MRI using T2-weighted imaging has been used for the work-up of prostate cancer, but is limited because of unsatisfactory sensitivity and specificity for prostate cancer detection and localization, especially when the cancer is located in the transitional and central zones, because cancer and normal tissues both have low signal intensity on T2-weighted images.
Huda et al. [30] examined the effectiveness of the ACR phantom to assess image quality in digital mammography and concluded that it is unsatisfactory due to an inappropriate range and sensitivity to characterise simulated breast lesions.
