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As a result, manipulating the lactation curve for improved persistency requires higher selection intensity than unrestricted selection based on 305-d estimated breeding value (EBV).
For de novo coiled coils, unrestricted selection of parameters allows the user to freely explore potential coiled-coil conformation space, but this is only useful if there is robust model validation to guide the users design.
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Based on this unrestricted model selection the model effects were tested for plausibility.
Diagnostic evaluation, antibiotic selection, and duration of therapy were predefined for the algorithm group, whereas clinicians caring for patients in the usual practice group had unrestricted choice of antibiotics, duration, and other aspects of clinical care.
The advantage of unrestricted index over conventional selection based on lactation EBV increases with increasing economic weight assigned to persistency.
By means of initially unrestricted group-wise probe selection we could specify probes separating S. flexneri as a Shigella subgroup (dashed box in Figure 1), though no special emphasis was put on such a subdivision.
The importance of environmental and spatial variables in explaining species composition was determined by an RDA analysis using Monte Carlo permutation tests (999 unrestricted permutations) followed by forward selection to remove the non-significant variables from each of the explanatory sets.
The exception was truncation selection 10, where unrestricted OCS only realised higher rates of genetic gain after time 45 (approximately).
The exception was truncation selection 10, where unrestricted OCS only realised more genetic gain after time 80.
Our reasoning was that, when we compared truncation selection 10 with unrestricted OCS, we saw the original motivation for OCS: sacrificing small amounts of short-term genetic gain can vastly reduce rate of inbreeding [ 1, 2].
Although restrictions with respect to inbreeding were imposed only for the classical selection scheme, the unrestricted IBD-GS scheme had lower average rates of inbreeding (1.04 to 1.13% vs. 1.25%) and new parents were recruited from more (26 to 29 vs. 20) of the 30 pre-selected families (Table 3).
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