Sentence examples for unresponsive mutant from inspiring English sources

Evaluation of endotoxin contamination using LPS unresponsive mutant and wild type macrophages.

Since DOPE gave false positive results in the chromogenic endotoxin assay, bone marrow derived macrophages (BMDM) from lipopolysaccharide unresponsive mutant mice (C3H/HeJ) were used to test contamination by endotoxin (Supporting Information Figure 1).

During development the DIF signalling system is turned on and btg is overinduced in the DIF unresponsive mutants (Fig. 3B).

U3A and U3C cells belong to the same complementation group of IFNα- and IFNγ-unresponsive mutants [ 17].

To confirm the B18R results, we took advantage of a human fibrosarcoma cell line, 2fTGH, from which interferon-unresponsive mutants have been isolated (Pellegrini et al., 1989).

The loss of NUAK1 activation by LKB1 (by using a NUAK1 NUAK1 mutant unresponsive to LKB1 or by inhibiting LKB1 activity in NUAK1 expressing cells) results in a failure of NUAK1 to induce senescence, thus demonstrating the major role of LKB1 in NUAK1-induced senescence.

Unlike the other targeted mutants, the cytosolic eNOS mutant was unresponsive to cAMP, indicating that membrane association and phosphorylation are required for eNOS activation.

Of the tested tad-locus mutants, only the ΔrcpA mutant was unresponsive to IL-1β.

Importantly, data shown in Figure 4 indicate that while the C16/20A RhoA mutant is unresponsive to ROS treatment, it is still capable of being activated and inactivated by other physiological stimuli.

Gene expression levels were normalised to the level of β-actin expression, which we have shown to be unresponsive to Kras mutation, and were reported relative to mutant Kras expression level in the scramble RNA-transfected cells.

During vegetative growth, when DIF signalling is inactive, the wt Ax2 and the DIF unresponsive dimB− and mybE− mutants express btg at comparable levels (Fig. 3A).