Sentence examples for unresponsive cells from inspiring English sources

Superposed CD28 costimulation results in remarkable high death rates on unresponsive cells (Figure 5D), which is even more pronounced in mixed cultures (p<0.001 vs isolated cells).

In these later cell lines, we showed that the synergistic effect was due, at least partially, to the recruitment of unresponsive cells into the expressing cell population.

In J-Lat cells, we showed that this synergism was due, at least partially, to the synergistic recruitment of unresponsive cells into the expressing cell population.

Given that all of the unresponsive cells in our panel do not demonstrate a TGFβ induced increase in transcriptional activity of a TGFβ reporter plasmid, defective Smad-mediated signal transduction is a possible underlying mechanism (Figure 3).

This implied that the synergistic effect observed following a prostratin+HDACI cotreatment on viral p24 antigen production was due, at least in part, to the recruitment of unresponsive cells into the responsive cell population.

To test if p63 still remains able to transactivate in these unresponsive cells, the ES-derived ectodermal cell line was cotransfected with ΔNp63 and a p63-responsive reporter construct [26].

However, among these unresponsive cell lines, 21 cell lines show either no expression or weak expression of T βRII.

Analysis of the IFN-γ receptors revealed a similar expression in both of the unresponsive cell lines (not shown).

In the present study we assessed the effect of GnRH on the invasiveness capacity of human breast cancer MDA-MB-231 cells, an aggressive, highly invasive, and estrogen unresponsive cell line [ 49].

To better examine the role of ER α on the Acrp30 effects we added ER α into the oestrogen unresponsive cell line MDA-MB-231 (MDA-wt) using liposome-mediated transfection.

The finding that surface CD40 expression was paralleled by accumulation of intracellular CD40 protein in rIFN- γ-responsive cell lines, whereas no intracellular CD40 was detected in unresponsive cell lines, suggest that the inability of the latter cell lines to express the CD40 protein upon incubation with rIFN- γ was not because of defects in protein trafficking.