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Both soluble and full-length TRAIL bind to their cognate cell surface receptors in the target cell to engage the apoptotic pathway (Ashkinazi et al, 1999) although the two TRAIL variants have been reported to possess different apoptosis-inducing capacities in cancer cells suggesting currently unresolved differences in their mechanism of action (Voelkel-Johnson et al, 2002; Seol et al, 2003).
Even so, Mr. Topolanek's comments during a speech to the European Parliament underscored unresolved differences.
There are major unresolved differences including over the future of Mr Assad.
While the latter has yet to be implemented because of unresolved differences, the IAEA process went smoothly enough for most of 1992.
But the governments also have unresolved differences on matters of trade, energy, water and the management of their 2,000-mile 2,000-mileder.
As it turned out the pair would meet on Centre Court before heading to actual court, and Ashe hinted at their unresolved differences when he turned up for the final in his Davis Cup warm-up jacket.
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The argument between husband and wife hovers in the air, an unresolved difference widened by all the small irritations that accumulate in a long marriage.
Behind the dispute about whether and how to help Greece, the most egregious violator of the European Union's fiscal rules, lies an unresolved difference between the founders of the Union, Germany and France, about the nature and purpose of the euro.
There is an unresolved difference between those, like Mr Keating, who want greater openness and others, such as Cardinal Mahony, who fear that the revelations are starting to undermine the church's legitimate work.As if the standing of the church could not fall any further, this week also saw the arrest of the bishop of Phoenix.
A yet unresolved difference in the number and the type of RM systems between commensal and dairy LAB has been previously observed [ 40, 41].
Also, all the discrepant results concerned largely exploratory subgroup analyses done within a framework of multiple significance testing and arguably, an α-level higher than 5% would be more appropriate: at α=1%, the only unresolved difference is for patients on β-blockers alone.
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