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We identified previously unrecognized variations in the fiber gene and E4 ORF 6/7 peptides among the various genome types of Ad7.
We propose that the major research focus in this area should be in the unused and unrecognized variations that have occurred after domestication.
For each position of the interrogated sequence, eight 25mer probes are represented on the array: four probes for each strand, each with a different nucleotide in the middle position (A, G, C, T); unrecognized variations were assigned as 'N'.
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In the present resequencing study, we show a considerable and previously unrecognized variation within the RPS19 gene locus.
This study has identified clinically unrecognized variation in cognitive and gait performance in middle age associated with potentially preventable covert cerebrovascular disease, which may indicate higher risk of future cognitive and gait impairment due to decreased cognitive reserve.
Other possible reasons for the deviations from HWE (particularly in controls but also in cases) may include residual technical issues with SNP assays and SNP calling, ascertainment bias, sample subdivision (stratification or admixture), and other unknown or unrecognized sequence variation confounding SNP assays.
We provide here a catalog of the considerable, previously unrecognized degree of variation in this region.
Because unrecognized DNA sequence variation near Prnp codon 211 may interfere with genotype scoring, it was important to sequence the complete Prnp coding sequence in diverse sires and dams from purebred collections.
But another possibility is that unrecognized species or population variation of this vector throughout southern PNG and northern Australia itself may limit the establishment of JEV.
Human data showed a remarkable degree of variability which might be due to between-donor variation or to unrecognized, subclinical affections of some blood donors.
Theory and simulations suggest that phylogenetic inference is particularly sensitive to unrecognized site-to-site rate variation [ 17, 18].
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