Sentence examples for unrecognized target from inspiring English sources
Like classic LTP, disinhibition-mediated LTP requires NMDAR activation, suggesting a role in types of learning and memory attributed primarily to the former and raising the possibility of a previously unrecognized target for therapeutic intervention in disorders linked to memory deficits, as well as a potentially overlooked site of LTP expression in other areas of the brain.
If hypogalactosylated IgG is pathogenic, then IgG glycosylation might represent an unrecognized target of DMARD therapy.
These findings shed light on previously unrecognized target molecules and pathways for cancer therapeutics.
Do the noted side effects hint at additional unrecognized target molecules affected by the used Syk inhibitor?
These results suggest that the BM is an important but previously unrecognized target organ in SLE with critical implications for B-cell ontogeny and selection.
Representative peak images of genes with Smad2 binding in multiple species are shown in Figure 2B, including the known Nodal target gene, lft1, and a hitherto unrecognized target and regulator of dorsoventral patterning, ddit4 [ 41].
Though more challenging to produce, antibacterial compounds that have novel structures, mechanisms of action and/or exploit previously unrecognized targets, as compared to those that have already reached the market, are the most logical choices for combating drug resistant pathogens (Donadio et al. 2010; Gwynn et al. 2010).
While earlier studies have identified CSF-1R and SRC targets phosphorylated in other cell types, some of which were detected in this analysis, previously unrecognized targets of these kinases were also revealed in this study.
This development has been greatly assisted by the advent of genomics and systems biology, which have led to the identification of previously unrecognized targets on bacteria.
High-throughput sequencing analysis of crosslinked RNAs revealed that the TRAMP complex marks its targets with a short oligo(A) tail and that Nrd1 Nab3 functions upstream of TRAMP and exosome in surveillance of a wide range of previously unrecognized targets.
Thus, renal epithelium constitutes a unique and previously unrecognized cell target for HIV-1 infection.
