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All peaks detected (unprocessed datasets) were used for the initial analysis.
The PLS-DA model built using unprocessed datasets showed a complete separation between the two groups.
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In our previous studies, the SE feature extraction was implemented on an unprocessed dataset [26, 27, 28, 29] with motion and muscle artifacts.
In the development phase, other researchers - as well as the dataset creator - would be able to discover and access a given unprocessed dataset without needing to wait for it to get processed and transferred into the final Chempound data repository.
The miR172, miR394 and miR408 families, which are transcribed in rice and are believed to regulate an APETALA2 transcription factor [ 43], a F-box protein [ 19] and a plantacyanin [ 44], respectively, are abundantly expressed in our unprocessed dataset.
Arrays derived from total RNA had higher Pearson's correlations than did arrays derived from amplified RNA when considering the entire unprocessed dataset, however, when considering a gene set of high signal intensity, the amplified arrays had superior correlation coefficients than did the total RNA arrays.
The mean attenuation values of the HYPR-LR-post-processed ULD dataset showed a higher correlation with the standard LD dataset than with the unprocessed ULD dataset (r = 0.672 vs. 0.542), but both correlations were significant (p<0.0001).
The electrocardiogram (ECG) was digitally recorded during data acquisition and was stored with the unprocessed CT dataset.
Both unprocessed and preprocessed datasets were used for PLS-DA.
No sufficient visual analysis of the normalized CBF, CBV, MTT and TTP perfusion maps was possible in the unprocessed ULD BPCT datasets (Figure 3).
Unprocessed gene-expression datasets, generated using a whole-transcript GeneChip platform (Human Exon 1.0 ST Array; Affymetrix Inc., Santa Clara, CA, USA), were downloaded from the GEO public data depository, deposited mainly by the ENCODE project[ 18].
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