Sentence examples for unpredictable toxicity patterns from inspiring English sources

This might explain the similar toxicity profile seen in the higher dose groups (from 24 mg m−2 onwards) and unpredictable toxicity patterns in this dose range.

Although intermediate doses of 30 and 33 mg m−2 were explored, no clear MTD could be identified as the toxicity patterns proved unpredictable.

Amonafide is a naphthalimide derivative with antitumor activity and has failed to enter clinical phase III, because of its high-variable and unpredictable toxicity.

Camptothecin (CPT) presents numerous challenges associated with optimal transport and delivery including variability in clinically observed effects, low target tissue concentrations and severe and unpredictable toxicity.

In addition, its soluble sodium salt can produce unpredictable toxicity (Gottlieb et al, 1970).

The failure (poor activity, unpredictable toxicity) of some new combinations may reflect a lack of rigorous preclinical investigation.

Such unpredictable toxicities are thought to be concentration-related, based on the offending dosages and impaired clearance in many affected patients.

The overall toxicity pattern was acceptable over the study course.

It is a truly gorgeous thing, its unpredictable flight patterns, the amethyst light on its wings.

They are often dropped by parachute, making them susceptible to unpredictable wind patterns.

This complexity gives rise to unpredictable failure patterns.