Over the last four decades, the annual earnings of the median man with only a high-school diploma declined by 46 percent – a decline unprecedented in duration and size.
Durability of clinical responses, unique to immunotherapy, was unprecedented (median duration of response was 74 weeks and 1- and 2-year OS was 42% and 14%, respectively) (Brahmer et al, 2013).
With more than 850 cases reported in Guinea, Liberia and Sierra Leone by the World Health Organization (WHO), this first-ever Ebola outbreak in West Africa has become a major regional threat, unprecedented in duration and in scale.
The judge reflected on the fraud's unprecedented scale, its duration over two decades and its thousands of victims.
James Heckman, a University of Chicago economist and Nobel laureate, in preparing a forthcoming book on the economic effects of human development, said in an interview that Dr. Weikart's work was unprecedented in the duration and intensity of its observations.
Thus, although the El Niño event of 2015/16 was indeed very large, there are no reports in the published literature to suggest that the unprecedented magnitude and/or duration of the Tasman Sea marine heatwave could be due solely to this event.
The collapse of the World Trade Center WTCC) on 11 September 2001 exposed New York City firefighters to smoke and dust of unprecedented magnitude and duration.
It happens that to examine long-term effects of modern hypnotics, pharmaceutical manufacturers have recently completed randomized trials of unprecedented size and duration.
The unprecedented scope and duration of the outbreak has left health workers struggling to keep up – and at serious risk themselves.
