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Given the recent unpleasantness between the two, and Mrs. Clinton's 10-state losing streak, it seems a safe bet that when they meet Thursday night in Austin, Tex., at a debate sponsored by CNN, the tone just might not be so jolly.
This crime wave was one important reason why the ownership and production of guns did not fall away after the "late unpleasantness between the states", as some Southerners put it.Another reason was that attitudes towards guns had already begun to change before the war began.
Higher levels of deactivation in left rACC were associated with less change in unpleasantness between warmth to mild pain in females but not so for males.
This apparent sex difference in the amount of change in reported unpleasantness between mild and moderate pain was confirmed with the statistically significant difference in those values.
While not statistically significant, females reported less change in unpleasantness between warm and both mild and moderate pain detection levels than did males with rather large difference effect sizes (Cohen's d = 0.76 0.78; see Table 2).
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Ratings of pleasantness vs. unpleasantness ranged between -10 indicating that pain stimuli were extremely unpleasant and 10 suggesting that pain stimulation was highly pleasant.
Greater BOLD signal changes in right (ipsilateral) SII were associated with greater increases in self-reported unpleasantness ratings between the moderate pain and warmth conditions across both females and males (beta = 0.43, p = 0.043; Fig. 11).
H0_3 In individuals with COPD, the relationship between immediate unpleasantness, discomfort and emotional affective response does not differ between dyspnea associated with activities of daily living (ADL) and experimentally induced dyspnea.
H0_2 During experimentally induced dyspnea, the relationship between immediate unpleasantness, discomfort and emotional affective response (A2 ) does not differ between healthy and COPD volunteers.
Price draws a distinction between immediate unpleasantness of a pain experience and what he calls pain's secondary affect, which consists of a conscious cognitive appraisal of the consequences of the pain and its cause, which involves various emotional reactions (e.g., worry, panic, anxiety, arousal, depression, etc).
At the neural level, we hypothesized a similar differentiation in neural activity between intensity and unpleasantness ratings.
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