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The utility of this model is that with the greatest fidelity possible, yet avoiding to end up with an unmanageable model, it represents the basic facts of the immune action solicited by an infectious agent.
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However, in formalising these relationships, this consideration will not only greatly complicate the issue, but will also make the model unmanageable, if not impossible to resolve.
Note: the more complex the analyzed system is, the more unmanageable the corresponding mathematical model for the computational experiments becomes.
This was felt to be leading to unmanageable pressure within the current model of 10-min consultations.
We restricted our parameter inference to two-population models (Fig. 2A) to avoid unmanageable numbers of parameters in a full six-population model.
The MST complains that this "market-based model" saddles farmers with unmanageable debts and poor land.
When Sykes arrived at Imperial in January, he found about 35 academic departments all reporting directly to him, a model he deemed totally unmanageable.
As an alternative to stepwise procedures, which would have introduced unmanageable noise into our analyses by introducing model selection uncertainty, we computed AIC for each of 726 multiple logistic regression candidate models.
We abstract from this in the model as it would add an unmanageable number of states.
Multivariable Cox regression models were initially attempted but proved unmanageable in terms of computer and time constraints, therefore Poisson regression was used for the calculation of MRRs, allowing inclusion of a primary baseline category of all other breeds.
ccomputing the ssaBIC for the bifactor model with adjustments for DIF was computationally unmanageable with MLR.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com