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Now they may finally have found a clue in an unlikely population: retired racing camels.
Our findings highlight the possibility of M. bovis infection in an unlikely geographic locale (Houston, Texas) to which bovine tuberculosis is not endemic and an unlikely population (cats and humans living in the same household).
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Moreover it is unlikely that population stratification would have confounded our results as we were able to remove population outliers from the analyses based on multidimensional-scaling using genome-wide genotypes.
If it reached Chicago's, which seems unlikely, its population would be about 2.5 million.
For these reasons, it seems unlikely that population stratification would have masked a causal association between CRP and CIMT.
Confounding is also unlikely, provided population stratification is properly accounted for.
However, we find it unlikely that population stratification has affected our results.
Thus, it is highly unlikely that population stratification has led to any false-negative results.
However for the case of Api m 6, it is unlikely that population structure strongly affects our conclusions.
The analyses not only fail to reject the null hypothesis, but also render unlikely a population effect size that differs greatly from zero.
However, it seems unlikely that population stratification is relevant here because the cases and controls were drawn from the same ethnic groups (both >98% of northwestern European ancestry).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com