The standard surgical treatment of symptomatic Meckel's diverticula is diverticulectomy, unless the indication for operative management is bleeding, in which case segmental resection of the ileum that includes both the diverticulum and the adjacent ileal ulcer should be performed [1].
These results have strongly influenced current international guidelines in that beta-blockers are no longer regarded as first line treatment of hypertension unless compelling indication and co-morbidities dictate otherwise.
We randomised patients either to routine care (control group), with catheters scheduled to be replaced every three days according to hospital policy, or to a group where the peripheral intravenous catheter was not replaced unless there was a clinical indication (clinically indicated group).
For practical and ethical reasons, patients with negative serology sometimes did not undergo a biopsy unless clinical indications of CD were evident.
Though it sounds possible to conclude that insulin glargine treatment can be deemed safe, the choice of an insulin treatment as initial therapy in type 2 diabetes may not be the most convenient one unless specific indications exist.
The differentiation between these different pathologic entities is important because no effective adjuvant therapy exists for cholangiocarcinoma, and unless clear indications of nonresectability exist, most patients should be considered for surgical exploration.
Unless the indications (including precise stage of disease) for using these drugs are clearly defined in advance, as well as the potential toxicities associated with long-term use, significant migration in costs and possible adverse events, as has occurred with existing conventional ADT, may ensue.
Our recommendation based on the findings presented within these articles, is that unless a specific indication for open reduction is present, we should always do a closed reduction attempt first.
Based on our findings, some recommendations can be done: 1. Anatomic reduction is one of the aims in the management of displaced SCHF, is in this sense that, unless a specific indication for open reduction is present, a closed reduction attempt should always be done first.
The investigators recommended goal hemoglobin concentration of 7 to 9 gm/dl, and not to transfuse for a hemoglobin concentration of greater than 9 gm/dl unless a specific indication was present.
