Sentence examples for unless activated by from inspiring English sources

In many cases CD44 does not bind to its ligand unless activated by external stimuli.

Mature triads of lymphatics, arteries, and veins are maintained in the adult unless activated by events requiring vascularization such as tumorigenesis [ 6].

In fact, three states of CD44 activation have been identified in cell lines and normal cell populations [ 16]: active CD44, which constitutively binds HA; inducible CD44, which does not bind HA or binds it only weakly unless activated by inducing mAbs, cytokines, growth factors or phorbol ester [ 4]; and inactive CD44, which does not bind HA even in the presence of inducing agents.

As shown in Fig. 7 a, wild-type αIIb β3 expressed on the CHO cell surface was in a low-affinity state and did not bind to fibrinogen significantly unless activated by mAb PT25-2, which brought up the binding by ∼33-fold.

In prokaryotes and eukaryotes, most gene-control systems are positive, meaning that a gene will not be transcribed unless it is activated by a regulatory protein.

Macklis's lab and others have found that in mice, newly born neurons play a unique role in learning novel odors and die unless they are activated by new, unfamiliar smells.

We find that PINs are unable to promote auxin efflux in this system unless PINs become activated by specific protein kinases of the Arabidopsis AGCVIII family.

The glmS mRNA is also unstable, unless its translation is activated by base-pairing with GlmZ sRNA [ 36].

Previous work has suggested that the ability of diazoxide to evoke currents from the KATP channel is dependent on MgATPase activity [ 11, 13] and the SUR2A subunit is not activated by diazoxide unless ADP is also present [ 21].

Unless certain view cells are activated by covert attention processes when the subject is not overtly viewing the associated "space out there," the response of the changing cells may not be assumed to be driven by input from the view cells associated with the target locations.

Our observation that IRF3 was not phosphorylated and activated by TBK1 unless the NEMO/TBK1 complex translocates from the mitochondria into the cytosol after the proteasomal degradation of MAVS suggests that the cytoplasmic translocation of the MAVS-assembled signaling complex is required for an optimal IRF3 activation.