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Importantly, PRRs also lie upstream of the inflammasome, in which caspase activation can unleash the function of inflammatory procytokines and initiate apoptosis or pyroptosis pathways, thereby coupling innate immune sensing of pathogens to host cell death.
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We find that the absence of Itk in the CD4SP OT-II transgenic thymocytes results in elevated expression of Eomesodermin, Granzyme B and Perforin, suggesting that reduced Th-POK expression may unleashed the function of Runx proteins in driving the expression of these genes (Fig. 11).
Since Bcl-2 controls the activation of caspase cascade by its interaction with Bax and by participation in apoptosome ensemble, degradation of Bcl-2 may unleash the inhibitory function of Bcl-2 over the apoptosome [ 26].
Using Nexmon, researchers can unleash the full capabilities of off-the-shelf Wi-Fi devices.
The stage was set to unleash the investment bankers.
This paper presented a comprehensive approach to fully unleash the energy savings potential of smart homes.
The resulting flares might unleash the observed energy.
Significant practical details must be worked through to unleash the full potential of acoustic monitoring.
The health sector has begun to unleash the transformational power of information and communications technology (ICT).
Disruption of Mcl1 Bak interaction would then unleash the mitochondrial outer membrane permeabilization (MOMP).
Time to unleash the symptoms!
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