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As the molecular mechanisms of PcG proteins in human cancers are largely unknown, understanding the tumour-suppressor function of PcG genes in Drosophila therefore could provide insights in human cancer biology.
As long as Burgess's musical side has remained largely unknown, understanding of his twin accomplishments has been incomplete … This book's primary aim is thus to examine this heretofore disregarded aspect of his creative life and, by doing so, reveal both halves of this remarkable dual artist.
Although the biologic features of tumor cells that exhibit VM remain unknown, understanding the molecular mechanisms that regulate VM is an important first step towards developing new vasculogenic therapies for glioma.
The impact of mTORC2 disruption on mammalian longevity is unknown; understanding the consequences of this inhibition will significantly inform the development of mTOR inhibitors as potential therapies for age-related diseases.
Competence varies widely within species, but the underlying causes are unknown; understanding the genetic architecture of competence in natural populations could lead to a better understanding of the evolutionary forces that maintain it.
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First-year 1G students reiterated the feeling of "unknown unknowns": of understanding that many resources are available, but often finding it difficult to locate specific points of access.
However, the impacts of co-exposure on aquatic organisms are virtually unknown and understanding the joint toxicity of ENPs and antibiotics is a topic of importance.
He was adept at planning long marches through unknown territory, understanding that he not only had thousands of men to manage efficiently, but that a huge amount of supplies were required to adequately feed and sustain his army.
Although at this time the mechanism of CMV inhibition is largely unknown, better understanding of it will have important clinical implications.
How miRNAs oncogenes and tumor suppressors function remains unknown, but understanding the mechanisms through which miRNAs contribute to tumorigenesis is of clear importance.
The roles and regulation of most xenobiotic metabolizing CYPs during development are unknown, impeding understanding of mechanisms of developmental toxicity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com