Sentence examples for unknown safety from inspiring English sources

In addition, studies will need to address the interaction of the fibers with the mucosal environment, including unknown safety and toxicity.

Almost 80% of potential drugs fail at the preclinical stage while an additional 85% fail during early-stage clinical trials, over half of which is due to previously unknown safety issues or lower efficacy than expected (Figure 2).

"Have we created another unknown safety risk?" The district will put the meat back into circulation if it finds that it is free of the filler, but like many districts, it is frustrated by the difficulty of determining what does and does not contain lean finely textured beef, which does not have to be listed as an ingredient.

This had the ambition of providing universal guidelines that would facilitate a preventive approach, rather than the reactive approach based on accident history (i.e. designing a system known to be safe, rather than reacting to events in a system of unknown safety).

Although recommendations are given in Eurocode to address the local buckling for the case of fire, few studies address its influence at elevated temperatures, and more particularly its influence on the load bearing capacity of laterally restrained beam-columns, which represents an unknown safety level for the Eurocode procedures.

As one official told me: "Even if we had the money, we wouldn't have the vaccine". Some doctors have also raised concerns about unknown safety risks, as no country has immunised large numbers of people.

The ultimate goal is to learn the behavior of an unknown, safety-critical dynamical system while controlling it at the same time — for instance, autonomously landing a passenger airplane that has just lost a wing.

However, the long-term effects of smart drugs on otherwise healthy brains were unknown, delaying safety assessments.

The purpose is to screen these records for evidence of currently unknown patient safety incidents (PSIs) e.g. a patient presents with an adverse reaction to a medication which was not 'allergy coded' when a similar reaction had occurred previously.

However, opponents highlight their unknown quality, safety and efficacy; their deleterious impact on the 'no smoking' health message; and their potential to harm children, including as a possible gateway to cigarette smoking [ 2, 4, 6].

Whether higher doses of mapatumumab would have led to more patients achieving a CR or PR is unknown, but safety data from other trials support further evaluation of higher doses.