The role of animal vectors in the life cycles and geographic distribution of these fungi is unknown; rodents have been suggested as possible reservoirs for Coccidioides, and birds and bats can carry Histoplasma, indicating that they may be capable of introducing microfoci in geographic regions not considered to be endemic (37 ).
The precise amyloid β-related mechanisms leading to cognitive dysfunction are still unknown, but rodent models of Alzheimer's disease typical amyloid β pathology show aberrant plasticity mechanisms (Walsh et al., 2002; Hsieh et al., 2006; Shankar et al., 2008; Li et al., 2009; Jo et al., 2011).
A single mandible from Porto Spanjo (one of the sites where fossils of A. donovani have been found), without preserved molars, differs from all Agathaeromys dentaries and is thought to represent an unknown different sigmodontine rodent.
Amongst the competing σ2 ligands, the pharmacokinetics of unlabelled SIG343 and SIG353 is unknown and limited in rodent studies, particularly in mice for haloperidol, and the only available pharmacokinetic data of haloperidol are those in rats [58] (terminal half-life of 1.5 h, intravenous bolus).
Studies have shown that glyphosate may interfere with fetal development and cause birth defects, and while much is still unknown, emerging work in rodent models shows that it has effects on male reproductive development.
This, however, is an artificial arrangement uniting groups for which evolutionary relationships to other rodents are unknown.
The fact that they are fairly common suggests that there must be a hitherto unknown mechanism that allows rodents to survive these virulent strains.
The relevance to humans of the pancreatic metaplasia observed with these agents in two of the rodent studies is unknown.
Horns are unknown among felines, pigs, dogs, rodents, bears, monkeys and apes.
In 1998, when Renger was in Japan, finishing his postdoctoral work, two groups of scientists announced almost simultaneously that they had identified, in rodents, a previously unknown neurotransmitter.
