Sentence examples for unknown retardation from inspiring English sources
While the actual size of the aggregated species responsible for Aβ neurotoxicity and fibrillogenesis mechanism(s) remain unknown, retardation of Aβ aggregation still holds assurance as an effective strategy in reducing Aβ-elicited toxicity.
Three brothers suffer from mental retardation of unknown cause.
Concerns about growth retardation and unknown effects on long-term brain development with stimulants have prompted interest in polyunsaturated fatty acid supplementation (PUFA) as an alternative treatment.
Initial estimates are that it represents ∼2% of all X-linked mental retardation of unknown etiology [14] [16].
CNAs are useful parameters for tumor classifications and – as recently introduced in genetic counseling procedures – as diagnostic tool for children with mental retardation of unknown origin [9], [10].
Symptomatic children included those with symptoms suspicious for IEM including metabolic acidosis, jaundice, hepatosplenomegaly, recurrent vomiting, hypoglycemia, hyperammonemia, mental retardation of unknown cause, language retardation, seizures and unconsciousness.
However, the mechanism by which defects on MCOLN1 function result on mental and psychomotor retardation remains largely unknown.
Such disorders are responsible for an unknown fraction of cases of mental retardation and autism as well as birth defects like a cleft palate or heart and kidney defects.
A prominent example of an RNA G-quadruplex binding protein is the fragile X mental retardation protein FMRP39, but it is currently unknown whether FMRP is sequestered by the C9orf72 expanded GGGGCC-repeats.
For most cases, the molecular basis of mental retardation with or without speech and language disorder is unknown due to the heterogeneity of underlying genetic factors.
Gene description/normal gene product: The gene product is FMRP, fragile X mental retardation protein, a widely expressed RNA-binding protein of unknown function found at highest levels in the brain and testes.
