The revelations, which are based on the discovery of previously unknown personal papers, are certain to come as a shock to fans of Swallows and Amazons (1930), a children's sailing adventure story set in the Lake District.
The exact mechanism of action of Riluzole is unknown; several papers have demonstrated its inhibition of sodium, calcium, potassium, and glutamate currents [ 3].
Genetics is a new science – you can plausibly date it from the rediscovery around 1900 of Gregor Mendel's then practically unknown 1866 paper on the breeding of peas, and the naming of the "gene" in 1909 as a discrete, stable, heritable unit – but its infiltrations into modern institutions and senses of the self are pervasive.
First, it is usually not clear to what extent the authors have tried to identify the unknowns; i.e. an unknown in one paper may be reported as an identified compound in another paper.
An unknown number of papers are also thought to have been stolen.
It's unknown how many papers and theses are ginned up under false pretenses.
Although this probably also has some influence on HER2 positivity rates found in different populations with GC, the relation between these factors and HER2 expression remains unknown, with few papers published [ 36, 37].
In 1972, a friend gave me a tip about the then-unknown Somerset Maugham papers in Yale University Library.
Their discoveries reverberate throughout the book: images of beautiful clothing on odd flimsy paper, unknown words like "awesome" and men with pretty hair.
They used 130 feet of iron pipe, 100 feet of wooden beams, more than 400 square yards of chicken wire, five gallons of paste, and an unknown quantity of paper.
