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There is, however, one important caveat to this generalisation: the essentially unknown importance of consequential impacts, and, in particular, indirect land-use change.
GHSR 1a is expressed mainly in the hypothalamus and pituitary [10], [11], whereas the GHSR type 1b mRNA expression has also been found in many peripheral organs [10], including immune cells [12], [13], indicating that ghrelin may have multiple functions in these tissues but with thus far unknown importance.
Bands of unknown importance that could represent truncated APC gene products were also found at approximately 180 and 110 kDa.
Transthyretin (TTR), a traditional biomarker for nutritional and inflammatory status exists in different molecular variants of yet unknown importance.
These dependencies often involve sets of sites with known functional relevance but also comprise other sites with unknown importance.
Together, these findings show that bilirubin is a molecule of diverse and currently unknown importance requiring further exploration [17].
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Although the biological functions of most miRNA are unknown, their importance for molecular regulation of differentiation, cell proliferation, and cell death has been demonstrated [7] [9].
These differences in scores at three and 12 months were small and of unknown clinical importance.
SNP rs2278422 resides in intron 8, a region of unknown biological importance.
While statistically significant, these findings are of unknown clinical importance suggesting a need for further research in this area.
Although this mutation is still annotated as one with unknown clinical importance in the BIC database, some studies support that it could be pathogenic [ 20, 27].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com