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This relative comparison was chosen because the moment of infection for contact-infected pigs is unknown, impeding the use of dpi.
The roles and regulation of most xenobiotic metabolizing CYPs during development are unknown, impeding understanding of mechanisms of developmental toxicity.
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However, unlike during controlled conditions in animal experiments, the precise time point of sepsis onset in patients is often unknown which impedes such treatment decisions for the caring clinician.
The effect so far is unknown; assessment is impeded by poor data.
The cost-benefit ratio of having more than one cambium might be the answer, although this has not been calculated to date, unless disadvantages as yet unknown to us would impede evolutionary spread of growth by more than one cambium.
Although natural mutants could be used for experimental models, the possibilities of homozygous embryonic lethality and additional unknown genetic changes often impede further analysis of the phenotypes and the physiological role of the gene.
Alternatively, mutations in the cytoplasmic loops may abrogate interactions with other, yet unidentified, protein partners or impede the yet unknown biochemical activity of the Mlo protein.
The underlying molecular mechanisms are still unknown, and investigations have been impeded by the complexity of brain connectivity and the need for experimental models allowing a fine manipulation of the local microenvironment at the subcellular level.
Unknown mutations in this core promoter may impede the seroconversion of HBeAg during antiviral treatment [ 18].
Thus, there might be unknown differences in GLs among species that impeded the detection of GL effects.
Furthermore, beneficial therapy in a life-threatening situation might be impeded, since, to date, it is unknown whether there is any evidence of a benefit of ASCT for some subgroups of breast cancer patients [ 23].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com