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'unknown etiology' is correct and usable in written English.
You could use it when referring to cause or origin of something that is unknown. For example: Scientists have been unable to determine the exact etiology of the disease, leaving the cause with an unknown etiology.
Exact(60)
Oral lichen planus (OLP) is a chronic oral inflammatory disease of unknown etiology.
Sarcoidosis is a systemic granulomatous disease with unknown etiology.
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder of unknown etiology in most cases.
Preeclampsia is a life-threatening perinatal complication with unknown etiology.
To identify risk factors for infantile cataracts of unknown etiology.
Lichen planus is an inflammatory skin disorder of unknown etiology.
Cancer is a complicated disease of unknown etiology.
This disease is currently known as CKDu, or chronic kidney disease of unknown etiology.
Juvenile idiopathic arthritis (JIA) encompasses a group of chronic childhood arthritides of unknown etiology.
Ito, Y. et al. Increased expression of perforin, granzyme B, and C5b-9 in villitis of unknown etiology.
The US military later issued a death certificate, seen by the Guardian, citing the cause of death as "cardiac arrest of unknown etiology".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com