Estimates for the range of P reserves differ rather to some extent because of unknown development parameters, such as an increase in food production and efficiency enhancement of fertilizer use [3 7].
Relating specifically to software, the FDA has given guidance in the past years for Commercial off the Shelf Software COTSS) and Software of Unknown Provenance (SOUP), relating to software that may be used as part of a medical device but with unknown development path and/or safety record [26, 48].
Nintendo, a company fiercely proud and somewhat conservative when it came to its products, took a punt on a new idea by largely unknown development team Game Freak.
Possibly because the pathogenesis of ALS remains mostly unknown, development of treatments that are effective across the spectrum of sporadic and familial ALS has not been achieved.
In this way, the scenario is to be seen as representative for unknown future developments in battery technology.
Although the evolutionary origin of two kinds of spores (dimorphism) is unknown, the development of megaspores in living plants suggests that differences in nutrition in the two kinds of sporangia are significant.
Despite the substantial risk of a $3.99 price tag and being from a relatively unknown app development shop, Monument Valley has been a huge and sustained success.
Prevalence is unknown and development can be acute or delayed [ 84].
It is unknown why development of the AA5x and hindbrain vasculature, but not ISVs, requires blood flow.
At the moment of writing, EASED comprises four disease classes (cancer, normal, healthy, unknown), four development classes (adult, embryo, newborn, unknown) as well as 193 tissue classes.
