Sentence examples for unknown constitutes from inspiring English sources

This phenomenon, whose pathogenesis is unknown, constitutes a challenge for the health care system, since clear diagnostic criteria are lacking [ 10], the symptoms do not correspond with objective measures of nervous system disease [ 11, 12] or with laboratory measures indicating inflammation [ 13- 15].

At the mechanistic level, how CGIs can function as mammalian PREs remains unknown, constituting a major gap in our understanding of how CGIs are functionally linked to the polycomb repressive systems in mammals.

That it's unknown what constitutes character and integrity among the league's owners.

Classifying the inhibiting, activating or toxicological potential of an unknown molecule constitutes a central aspect in cheminformatics.

Currently case-management programmes are being developed and evaluated worldwide for patients with multiple diseases, but it is still largely unknown what constitutes optimal care for multimorbid patients [ 10, 32].

At present, the clinical utility of changes in retinal vascular architecture is limited, as it remains unknown what constitutes an abnormal or pathological value of these retinal vascular parameters.

Proteins acting on carbohydrates and proteins of unknown function constituted the two most abundant classes.

The evolutionary processes governing the divergence of animal genitalia are mostly unknown and constitute one of the most intriguing pieces of a mayor puzzle that is speciation [ 1- 5].

Aside from well characterized stress response genes, about 2000 genes of unknown function, constituting 30% of the genes predicted in the genome, were affected.

We demonstrate how these "unknown knowns" constitute uncomfortable knowledge because they disrupt the simplified worldview that underpins contemporary discourse on the potential misuse of synthetic biology by malign actors.

In view of their prominence in the representative profiles and co-expression networks, these unknown genes constitute a new source for future studies on their roles in biological processes and potential involvement in determining HIV-1 susceptibility and resistance.