Sentence examples for unknown alterations from inspiring English sources
In addition, radiation induces other unknown alterations.
Thus the ccB signature may reflect the transcriptomic impact of these poor prognosis alterations, but more than one alteration may be necessary to establish this phenotype, and as yet unknown alterations are also likely to contribute.
Using WGBS of lymphoblastoid cell lines (LCLs) obtained from an ICF patient harboring mutated DNMT3B and one healthy control, we unraveled changes in DNA methylation at base-pair resolution and determined yet unknown alterations associated to the disease phenotype.
Thus, the differential MAMP receptor levels and/or yet unknown alterations in other signaling components between genotypes may determine the sensitivity of the system in signal relay from PBL1 to the MAPKs and other downstream events.
Thus RASopathy-associated switch III mutations do not show changes in nanoclustering, but may have unknown alterations (N-rasT50I, Figure 5 and [ Cirstea et al., 2010]; K-rasV152G, Figure 6; K-ras-E153V and K-ras-F156L [ Gremer et al., 2011; Mazhab-Jafari et al., 2015]).
The loss of iodide uptake capacity in poorly differentiated thyroid carcinomas is mainly due to the reduced/lost functional expression of the sodium/iodide symporter (NIS), with a defect occurring mainly at gene expression level, but in some case involving post-transcriptional or other unknown alterations [ 4- 7].
A number of similarities between RA and PGIA suggest that certain as-yet-unknown alterations of the immune system exist in both humans and mice.
New subtypes of cancer have been identified, or at least attributed to previously unknown genetic alterations, allowing a more nuanced approach to treatment.
Indeed, cancer is a complex disease characterized by the accumulation of several and often unknown molecular alterations that cause genetic instability, cell proliferation, and acquisition of an increasingly invasive phenotype resistant to therapeutic treatments.
More importantly, while it is unknown whether alterations in synaptic plasticity in VTA dopamine circuitry causatively contribute to drug addictive behavior, our findings strongly suggest a pivotal role of LTD in VTA dopamine circuitry in the development of cannabinoid-associated addictive learning.
Four previously unknown missense alterations were observed, which may be associated with the disease phenotype.
