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Chromosomal translocations and genomic instability are universal hallmarks of tumor cells.
Glycosylation changes are universal hallmarks of malignant transformation and tumor progression in human cancer, and can occur either across the entire cell or on specific molecules.
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Thirstiness is a universal hallmark of life.
Even more striking is the universal hallmark of all artiodactyls, the "double-pulley" astragalus in their ankles, which allows them to have very flexible fore and aft motions of their foot (but prevents lateral rotation).
One universal hallmark of ageing is the marked alterations in cellular energy metabolism [4].
We also reported that alternative splicing is a universal hallmark of the periostin C-terminal region.
A universal hallmark of cancer cells is the change in their glycosylation phenotype.
Loss of its nuclear immunopositivity has been demonstrated to be a nearly universal hallmark of malignancy [ 51].
In summary, the aggregation of transcript data suggests that the occurrence of alternative splicing is a universal hallmark of this part of the periostin gene.
An universal hallmark of cancer cells is the change in their glycosylation phenotype, with several effects on this tumour cells behavior [ 3].
Whatever the reason, the idea of aging as a universal hallmark of life, even affecting bacteria, was considered but dismissed in the 1950s and 1960s [ 8– 13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com