Sentence examples for universal differentiation from inspiring English sources

Embryonic stem cells, which exhibit a universal differentiation capacity, could theoretically differentiate into any mature tissue cells[1], [2], [12].

Recently, studies of the adult stem cells provide ample evidence that chromatin remodeling functions in universal differentiation events [32].

Such universal differentiation at a single locus is consistent with the action of a gene that generally sorts individuals into phenotypic classes and breed groups.

In developing a universal cardiac differentiation system, we evaluated and tested the strengths of multiple published protocols with a multivariate strategy.

The development of a universal cardiac differentiation protocol that can translate across multiple pluripotent stem cell lines allows immediate application to genetically diverse hiPSC lines created from patients with cardiac related diseases (e.g. long QT syndrome [50], [51]).

We used this data to develop a universal cardiac differentiation system that has an average efficiency of 94.7±2.4% hEB contracting for a diverse repertoire of hESC lines and hiPSC lines, including those generated from fetal fibroblasts using lentiviral methods, or neonatal CD34+ cord blood cells and mature-donor dermal fibroblasts using non-viral episomal-based methods.

Second, we sought to understand if the potential welfare effects are universal, taking into account differentiation across the birth cohorts and the within-cohort heterogeneity.

The finding of non-random universal patterns of phylogenetic differentiation suggests that similar evolutionary forces drive diversification across the broad range of scales, from macro-evolutionary to micro-evolutionary processes, shaping the diversity of life on the planet.

This efficient and cost-effective universal system for cardiac differentiation of hiPSC allows a potentially unlimited production of functional cardiomyocytes suitable for application to hPSC-based drug development, cardiac disease modeling, and the future generation of clinically-safe nonviral human cardiac cells for regenerative medicine.

Previous analyses of the topological properties of phylogenies have revealed universal patterns of phylogenetic differentiation [ 3, 6, 7, 11, 12].

Based on a universal criterion of C-genome differentiation, our study in phylogeny and molecular dating showed that D- and E-genome were tied together as sister group, but they diverged much earlier than CCDD tetraploid formation.