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Soil is another potential source of infection in healthy subjects as demonstrated by the universal colonization of soil with NTM in Finland [ 10] and supported by a skin test study of healthy persons in Belle Glade Florida [ 5].
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Universal screening for colonization by group B streptococcus (GBS) is the recommended strategy to reduce incidence of colonization in newborns and prevent neonatal GBS-related disease.
Since exposure to hot water sources is almost universal and since colonization of water systems is common, it would be difficult to design a conventional epidemiologic study to confirm water exposure as a transmission risk.
Thus, it is nearly impossible to define a universal standard for intestinal colonization and development of the intestinal microbiota.
Nevertheless, one may reasonably conclude that Candida colonization is almost universal.
In an effort to control the spread of MRSA, the VA health care system implemented a nationwide surveillance program [ 2, 7], which included universal nasal surveillance for MRSA colonization, contact precautions for patients carrying MRSA, and emphasis on proper hand hygiene.
Simultaneous colonization at multiple body sites with such pathogens is universal among ICU-patients (Bonten et al., 1996).
Even though the universal screening is not a resolved issue, knowledge of the magnitude of colonization is invaluable for planning to control the pathogen.
(A ) DNA was extracted from fecal pellets of media-gavaged mice and P. copri -gavaged mice 2 weeks after colonization and assayed by QPCR with P. copri specific primers compared to universal 16S.
Thus, targeting patients at risk of colonization at ICU admission may be worth further assessment as an alternative to universal screening.
(A ) DNA was extracted from fecal pellets of media, P. copri, and B. thetaiotamicron gavaged mice 2 weeks after colonization and assayed by QPCR with P. copri or Bacteroides specific primers compared to universal 16S amplicon.
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