The functions of the C-terminal proline-rich linker (L), the Dsg-specific repeated unit domains (RUDs) and the desmoglein terminal domain (DTD), which are all only present in desmogleins, are not clear (Dusek et al. 2007b).
Using a unit-domain matching heuristic reduced the number of term-mapping candidates by a mean of 71% even after other heuristics were used.
The ECDs can therefore be divided into two functional units: domains I to III, containing ligand binding and key dimerization controls, and a functionally distinct domain IV.
In conclusion, biologists need a description scheme for the biological process that allows detailed and formalized annotations at different levels of abstraction compatible with the structural organization of the functional units (domains) of proteins.
The uranyl-stained PB-PEO BCPs implied the brighter domains of 20 30 nm in diameter were PAP aggregates and the number of the unstained domains per unit area also increased at higher mCPR ratios (Fig. 4b).
Recent nuclear magnetic resonance (NMR) studies of AcSp1 repeats from both Nephila antipodiana and A. trifasciata delineate different domains in each repeat unit, one domain that is rich in alpha helices and one that is not [ 24, 25].
To identify a minimal structural unit of domain III needed for [3H]Etn incorporation, we generated deletion mutants of domain III and analyzed their expression and labeling with [3H]Etn.
Therefore, for parsimony, mean unit weighted domain scores were used for subsequent analysis and reporting (i.e., giving equal weight to items in calculating domain scores, and equal weight to domains in calculating factor scores).
We discretize (1.1) on the unit spatial domain (Omega=[0,1]^{2}) and the time span (I=[0,1]).
In this section, we conduct numerical experiments with two examples both on the unit square domain (Omega = 0,1 times (0,1)).
