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It is therefore tempting to speculate that in addition to unique P-box and D-box sequences and to a spatial expression uniquely restricted to photoreceptors, NR2E3 dimer formation can increase target specificity when compared to NR2E1, another NR expressed in the retina [12].
Furthermore, the uniquely restricted host range of RRV-pseudotyped vectors may aid in the design of novel cell-selective transduction strategies.
To determine if the HBV/E strains that are uniquely restricted to the HBV/E crescent are adapted to the populations in that region, we calculated overall and site-by-site selection pressures acting on the four ORFs in the 47-HBV/E whole genomes.
These results show that regulation of CTGF and TSP-1 by miR-18a and miR-19b is uniquely restricted to the cardiomyocyte.
These results imply that the age-related regulation of CTGF and TSP-1 expression by miR-18a and miR-19b in the heart is uniquely restricted to the cardiomyocyte to control its surrounding ECM.
Dedifferentiation of fully differentiated cells is not uniquely restricted to malignant cells, but upon damage or imbalance in tissue homeostasis, also normal mature cells can reprogram into a stem cell.
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In the case of human immunodeficiency virus (HIV) in resource-rich settings, a combination of measures including baseline resistance testing, potent regimens with high genetic barrier, close surveillance of therapy success, and introduction of new drug classes has been uniquely successful in restricting the prevalence of transmitted drug resistance (TDR) to levels below 10%15%% [ 1– 3].
Smchd1 has a role in the expression of several autosomal gene clusters that are subject to monoallelic expression, rather than being restricted to functioning uniquely in X inactivation.
If the Bowtie alignment was restricted to only uniquely mapped reads (i.e. any read aligning to more than one region of the genome is discarded), there was a significant reduction in the number of aligned reads, with more than 96% of the total reads being discarded in the most severely affected sample.
Hox genes are organized in a cluster, yet they are uniquely regulated in a spatially and temporally restricted manner such that each gene can contribute to a unique segment identity.
The lens rigidity problem we study is the following: Given M and D, do σ and ℓ, restricted to D, determine g uniquely, up to a pull back of a diffeomorphism that is identity on ∂ M ?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com