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Others have shown that TGF-β and IL-21 uniquely promote the polarisation of TH-17 cells from human naive CD4+ T cells, and further that IL-1β together with IL-6 or IL-23 are only capable of inducing TH-17 cells from human memory CD4+ T cells [ 9].
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Calmodulin (CaM) uniquely promotes signaling by oncogenic K-Ras, but not by N-Ras or H-Ras.
There is little evidence to support the notion that it uniquely promotes tolerance, and growing evidence that it is ineffective in the setting of allosensitization.
Here, we show that in contrast to the β-arrestin-biased agonists TRV120023 and TRV120026, membrane stretch uniquely promotes the coupling of the inhibitory G protein (Gαi ) to the AT1R to transduce signaling.
During this latter period, Stat3 uniquely promotes the death of MEC through apoptosis.
Among RBRs, the RING2-LDD uniquely promotes linear ubiquitin chain formation.
It manifests its anti-apoptotic effects by inhibiting various caspases and also uniquely promotes cell mitosis and proliferation [ 22- 24].
We do not yet know how LynA uniquely promotes downstream signaling, but we speculate that some activity of LynA may protect PLCγ from inhibition by Dok-3.
Importantly, the binding of RHAMM to HA fragments is surprisingly size specific: a mixture of 4 20 saccharides promotes endothelial cell migration through RHAMM but HA-6 present in this mixture uniquely promotes wound closure, M1 and M2 macrophage influx into wounds, and TGF β-1 production through RHAMM and CD44 [ 56, 123].
Our initiatives and advocacy work target critical situations where we are uniquely equipped to promote lasting change.
TPH cells appear to be uniquely poised to promote B-cell responses and antibody production within pathologically inflamed non-lymphoid tissues.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com