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Chimeric integrin molecules consisting of the α4 extra-cellular domain and a variety of α subunit cytoplasmic domains reveal that while a number of α subunit cytoplasmic domains can substitute in cell adhesion, the α6 and α5 cytoplasmic domains are uniquely necessary for FN assembly [14].
By symmetry, this same evolutionary theory leads to the expectation that the W chromosome may concentrate genes that are uniquely necessary for female fertility [ 30, 31].
We asked whether the intact oxLDL particle was uniquely necessary for its molecular signaling (31) or whether one of its chemical components could substitute for oxLDL.
Genetic analysis indicates that lg1 and lg2 are uniquely necessary for ligule and auricle development and play different roles in the ligule auricle induction mechanism.
Both the 5′ ss of intron 1 and branch point of intron 2 are uniquely necessary for circular RNA biogenesis under the lariat model, which predicts that deleting either of these sites should disrupt circularization.
Taken together, our observations suggest a model whereby the KH domains of FMRP are necessary for an action on polyribosomes that can be compensated for by FXR1/2P, but that the FMRP RGG box is uniquely necessary for stress-related transition from polyribosomes to stress granules.
Similar(6)
The intellectual quest for ways to ground American power is vital, for him, because America is uniquely necessary to the world.
God is simple existence as He is uniquely necessary in and by Himself.
Our studies show that Mafb promotes a key feature of the SGN identity, namely the formation of the uniquely large post-synaptic terminals that are necessary for the sense of hearing.
P. gingivalis is a prokaryote that uniquely contains a peptidyl arginine deiminase enzyme [ 17] necessary for citrullination and can induce an immune response to citrullinated self-proteins [ 16, 18].
I present an Aristotelian argument that the political association uniquely allows for the exercise of legitimate rule and provides for resources necessary for a truly flourishing life.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com