The molecular mechanisms by which P. falciparum regulates the rate of sexual conversion have been difficult to characterize globally due to their uniquely host-specific nature and the corresponding lack of good in vitro or animal model systems.
Furthermore, the uniquely restricted host range of RRV-pseudotyped vectors may aid in the design of novel cell-selective transduction strategies.
We find that the intracellular bacterial pathogen Legionella pneumophila uses a Dot/Icm type IV secreted effector, RomA, to uniquely modify the host chromatin landscape.
The genes responding uniquely in each host were examined further.
Similarly, analysis of RPE flatmounts subsequent to the transfer schemes outlined in Figure 5A, revealed that microglia accumulated uniquely when the host was deficient in SUCNR1.
It has been recently suggested that NEC is associated with a marked inhibition in both enterocyte migration and proliferation, making the host uniquely susceptible to further injury and finally to bacterial translocation [ 12].
The O-antigen chain of H. pylori is uniquely decorated with host-related Lewis antigens, carbohydrates that are also expressed by the gastric epithelium in humans.
In particular, the unparalleled numbers and diversity of the arthropods, combined with the wealth of parasitic lifestyles that arthropod species display, may mean these animals are uniquely placed as hosts and carriers of viruses to act as a hotspot of viral evolution.
The Internet is continuously evolving from a static, host-based, uniquely attached node model to a mobile, host-free node model with the possibility of multiple attachment points to the network.
Since the mass shooting that killed 17 people made Parkland the latest city to host a uniquely American spectacle of carnage, the nation has watched the teenage survivors take control of the gun control debate.
Furthermore, our work highlights the fact that HQT uniquely interacts with the host immune system to exact its immunoregulatory potency.
