On the other hand, subsets of the genome significantly differ in the amount of phylogenetic history they share with one another [ 26], and their genes have uniquely different functions and constraints.
Allele E1bii differs uniquely from all other alleles at a nonsynonymous site in the prepro region of the transcript, the only substitution observed outside of the toxin coding region.
The functional characteristics of components of the ERP are well understood, and some components represent processing that may differ uniquely from individual to individual such as the N400 component, which represents access to the semantic network.
It is noteworthy that step 1, as implemented, excluded sites in which the reference allele differed uniquely from the alleles represented in the discovery panels.
Since our study compared genetically matched lines differing uniquely in one LQT2 point mutation, a clear genotype phenotype relationship could be ascertained.
The choice of the primers was based on the presence or absence of exons 6, 7, 8 and 9 which differs in different variants uniquely.
The number of reads that mapped uniquely for given samples differed as much as approximately 2-fold between the largest and smallest totals (Additional file 7).
Extending the calculated pairwise SNP density to the approximately one third of the sorghum genome that is uniquely alignable suggests that Sb2 differs from BTx623 at around 250,000 and Sb8 at nearly 600,000 SNPs.
Similarly, as the picture of health needs that these youth may face may be more complex than what might be addressable within the justice system, these data also suggest that comprehensive, multi-level services, such as the Wrap-around work pioneered by Karl Dennis [e.g., [ 63]], might be uniquely able to address the differing, but equally important needs of these high-risk youth.
The phospholipids found uniquely with each connexin tended to differ from this pattern, which could suggest that changes in the ratio of PE to PC could modulate the channels via changes in negative membrane curvature.
