Your English writing platform
Discover LudwigExact(40)
Nonetheless, despite the overall high level of binding conservation, the increase in conservation at commonly bound sites compared to uniquely bound sites, with 94% of commonly-bound D. simulans sites being conserved in D. melanogaster, is striking and highly significant.
Gene ontology analysis of targets which are uniquely bound by MYCN in the over expressing state revealed enrichment for DNA helicases and mRNA transcriptional regulation, amongst others.
In the latter case, bands uniquely bound to GST-ErbB4 were further analyzed by Mass Spectrometry using API QSTAR™ Pulsar Hybrid LC/MS/MS System.
Approximately 80% of the bound genes that had homologs in the second species were uniquely bound in the first species; only a fifth of the bound homologous genes shared E2F4 binding between species.
Interestingly, DNA packaging, which has been suggested to be a function of E2F4 in murine cells [27], was enriched as a functional category in the genes uniquely bound by E2f4 in mouse (Figure 2D, Figure S7).
KEGG pathway analysis revealed a shortlist of genes whose promoters uniquely bound MYCN in the over expressing state and who are members of established signalling pathways which are dysregulated in cancer.
Similar(20)
"And, yeah, I've hung out with Jakob Dylan, Sean Lennon and Ziggy Marley too, but there is nothing that uniquely binds us.
While BoNT/B and G share the synaptic vesicle proteins synaptotagmin (Syt) I and Syt-II as protein receptors, BoNT/A uniquely binds SV2.
This singular choice to bring children into the world uniquely binds us to one another, not for 18 years, but for life.
EWS/FLI1 and EWS share some protein partners such as BARD1 [ 71] but uniquely bind others, such as YB1 [ 50].
In contrast, hTFIIEα AC-D uniquely binds to p62 PH-D through its core structure together with its flexible N-terminal tail.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com