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No compound-specific or unique toxicity was identified.
Hepatobiliary toxicity seen with motesanib emerged as a unique toxicity with an unknown etiology.
Patupilone has a unique toxicity profile with little or no haematological toxicity and limited neurotoxicity, but significant gastrointestinal toxicity, primarily diarrhoea.
A Venn diagram analysis was performed first to identify common and unique toxicity pathways that were affected by different U concentrations.
BCG's activity appears to be strictly localized and as a living organism, BCG poses unique toxicity problems associated with its use.
It also produces a unique toxicity among anesthetic drugs: inhibition of adrenal steroid synthesis that far outlasts its hypnotic action [ 20].
Similar(52)
Unique toxicities are associated with cytotoxic chemotherapy and with endocrine and HER2-targeted therapies.
We designed the PPB (paclitaxel, pemetrexed, and bevacizumab) regimen to maintain or improve outcomes while averting the unique toxicities of platinum-based chemotherapies.
Humanized monoclonal antibodies (MoAbs) have unique toxicities that differ from those of traditional chemotherapy.
However, despite a few unique toxicities, the safety profile proved very comparable with standard intensive chemotherapy regimens.
In addition, the anticancer agents, RAD001 or AP23573, are associated with a number of unique toxicities, with one of the most significant being the so-called painful mTOR inhibitor-associated stomatitis (mIAS) [ 78].
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