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Although our study has found a unique progression in MT thickness changes and provided a promising technique for clinical assessment of LHON, further study is warranted.
Remarkably, phylogenetic analysis suggests that the shift from unicellular to multicellular organisms with differentiated cells was not a unique progression in the evolution of life, but it was, in fact, a frequent event [ 1- 4].
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There are few orthopoxvirus animal disease models that simulate the pathophysiology and unique clinical progression of smallpox and monkeypox in humans.
In summary, our findings show that H2Bub1, H3K4me2, and H3K79me2 exhibit unique temporal progression patterns throughout the cell cycle.
DCM in Doberman Pinschers is inherited and typically shows a unique disease progression with a late onset [ 1, 4- 8].
This may represent the unique physiological progression of radixin from the pre-neoplastic state to the neoplastic state.
New response criteria were developed for clinical trials of brain tumors by incorporating T2 and FLAIR changes on MR imaging to evaluate the unique infiltrative progression pattern of malignant gliomas [ 83].
We speculated that the cancer progressed by mural metastasis, and this unique pattern of progression might be affected by infiltration of IgG4-positive plasma cells.
Could you discuss this? —Susanna, Liberia; Cheryl, Westchester City. A. Although we think of Alzheimer's as a single homogenous disease, it's more accurate to think of it as a constellation of closely related diseases with each genetic defect resulting in a unique pattern of progression depending on brain areas affected.
This unique "stepladder" career progression may also be a motivator.
However, relatively little is known about whether RTT mouse models recapitulate the unique features of progression, regression and stabilization that define the human disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com