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Description of the strands and loops is according to the IMGT unique numbering for C-DOMAIN [ 42 ].
Leader region (L-PART1 + L-PART2), CDR-IMGT and FR-IMGT are also indicated, according to the IMGT unique numbering for V-DOMAIN [ 27 ].
The description of the strands and loops and of the FR-IMGT and CDR-IMGT is according to the IMGT unique numbering for V-REGION [ 27 ].
The deduced amino acid (AA) sequences of the sheep TRAV genes were manually aligned according to IMGT unique numbering for the V-REGION [ 27] to maximize percentage of identity (Additional file 6).
Rearranged CDR3 lengths were determined from positions 105 to 117, that is, between the 2nd-CYS 104 and J-PHE 118 of the FGXG motif, according to the IMGT unique numbering for V-DOMAIN [ 29].
The deduced AA sequences of the sheep potential functional TRDV genes and in-frame pseudogenes were also manually aligned according to IMGT unique numbering for the V-REGION [ 27] (Fig. 2).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com