Your English writing platform
Discover LudwigSuggestions(4)
Exact(6)
Applications range from combining two drug activities into one molecule to unique modes of action like the recruiting of immune cells to tumors.
Development of new therapies is urgently needed, either by finding new compounds with unique modes of action, or by reversing resistance towards known drugs with 'chemosensitizers' or 'chemoreversal' agents (CRA).
This flexibility provides an opportunity to increase activity, prevent the development of resistance, or introduce unique modes of action that are otherwise not attainable via standard monoclonal antibody formats targeting a single antigen.
Not only are these molecules likely to be different from those extracted from land-based plants and bacteria, but they're also likely to have "unique modes of action," maximising their chances of making it to market and becoming best-selling drugs.
Combining agents with unique modes of action may improve outcomes and overcome chemoresistance without significantly increasing toxicity.
A combination of AP and quantitative MS was also used recently to examine the target-binding specificity of 16 different histone deacetylase (HDAC) inhibitors that have therapeutic potential as anti-cancer drugs [ 80], with the differences in observed binding profiles supporting unique modes of action.
Similar(54)
Products that contain a.s. with a similar mode of action were clearly underrepresented, while the diversity among products with dissimilarly acting a.s. was very high given that already 34 products represented a unique mode-of-action combination.
But the number of cases of liver failure was small compared with the 1.9 million people who have taken the drug at one time or another, and the F.D.A. initially decided to keep Rezulin on the market despite the risk, because it had a unique mode of action and did help many patients.
Ryanodine receptors (RyRs) activator has become one class of popular insecticide because of its unique mode of action.
The isoprenoid brasilicardin A is a promising immunosuppressant compound with a unique mode of action, high potency and reduced toxicity compared to today's standard drugs.
The results showed no enhancement of the antimalarial activity of the dual molecules but evidenced a unique mode of action of ferroquine and ferrocenyl analogues distinct of those of chloroquine and nonferrocenic 4-aminoquinoline analogues.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com