Due to the unique localization of A-RAF to endosomes, this delay is optimal for regulation of later endocytic events such as recycling of receptors [51].
In this paper we propose primitives for unique localization of nodes in a sensor network.
This unique localization of TJ proteins could possibly function as a gate which controls the passage of ions and solutes between the cytoplasm and the vesicular lumen, and as a fence which differentiates between transmembrane proteins of the apical and basolateral membranes.
To determine if differential vascularization of tumors could be responsible for unique localization of HCAb2; CD31 and HCAb2 staining was performed on a 24 h tumor section (Fig. 7a- h).
If three anchors belong to the same petal, the center of the petal can collapse its petal, and therefore the sepal completely, which further enables the unique localization of every petal in the graph and the whole network is uniquely localized.
To determine if unique localization of HCAb2 was due to differential expression of HSP90 in tumor cells, a 24 h time point tumor section was probed with a commercial anti-HSP90 and Alexa Fluor® 488 anti-mouse IgG antibodies.
The unique localization of CD55 at the edge of the synovial tissue, conjugated to collagenous fibers, implied a possible role of CD55 in protecting the synovial tissue from attack by complement.
Although still nuclear, this unique localization of Brdt protein was lost in Brdt∆BD1/∆BD1 mutant spermatids and Brdt and Sirt1 overlapped around the chromocenters.
These anti-neuronal antibodies bound to the optic nerve and brain proteins but not to retinal antigens, which is in agreement with the unique localization of those myelin proteins in CNS tissues, including optic nerve (not shown).
In addition to the kinetics of the migration of MGL2+ DDCs from the dermis to the LNs, the unique localization of MGL2+ DDCs within the LNs supports our hypothesis that MGL2+ DDCs are the predominant APCs in CHS.
