Sentence examples for unique gene expression programs from inspiring English sources

Nonetheless, both MLL1 and MLL2 regulate many unique gene expression programs above and beyond genes that are directly H3K4-methylated.

A subfamily of muscle identity genes encoding HD TFs (referred to herein as 'founder cell identity homeodomains' or FCI-HDs) has been proposed to control the unique gene expression programs of individual FCs (Baylies et al., 1998; Jagla et al., 2001).

Here, we used an integrated genomics approach to interrogate the molecular mechanisms of action of a subset of identity HD TFs that have been proposed to control the unique gene expression programs of muscle FCs (Baylies et al., 1998; Tixier et al., 2010).

Thus, it is the coordinated expression of fiber-type-specific gene expression programs that gives each fiber type its unique contractile and metabolic properties.

Further characterization of complex TF interactions in the simple and genetically tractable Drosophila model opens a unique avenue to deciphering the contribution of TF cooperation and aberrant gene expression programs during malignant transformation.

The coordinated expression of fiber-type-specific gene expression programs is necessary to give each fiber type its unique contractile properties.

Further studies of the gene expression profiles of other purified leukocyte populations such as NK cells and monocytes will help establish the specialized gene expression programs that enable each cell type to perform its unique function, and will further improve our ability to reconstruct the cellular composition of heterogeneous samples.

This unique model system, in which samples were matched for genotype and topology, allows identification of gene expression programs predominantly influenced by AR signaling, likely during genital morphogenesis.

This further supports our hypothesis that the gene expression programs that are transcriptionally active in the various subtypes of childhood leukemia are unique to the leukemia and show limited similarity to other tissues and human cancers.

Human cancer is characterized by somatic copy number alternation and unique gene expression profiles.

Several studies have identified unique gene expression signatures characteristic of various hematologic and non-hematologic cancers.