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"Sheila had unique relationships with each of her children and losing her would have left a unique gap in each of their lives, which each of them had to handle in their own way".
We show that TBCC is a unique GAP for which affinity depends on αβ-tubulin binding onto TBC-DEG.
Lambda.pl first estimates the number of unique gap characters, and from which, assuming a Poisson distribution, it infers the ratio between indel and substitution events.
We used the polymorphic membrane protein H gene (pmp gene) as a PCR target because it has a unique gap in LGV strains of C. trachomatis, compared to other serovars, which makes it highly specific.
Human DNA polymerase κ (Polκ), a member of the Y family of lesion bypass polymerases, is specialized to bypass bulky DNA minor groove lesions in a predominantly error-free manner, by housing them in its unique gap.
In the molecular diagnostic of lymphogranuloma venereum targeting the pmp-H gene has predominated as all the LGV-serovars possess a unique gap of 36 nt which is absent in the other serovars.
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The resultant 15,500 base pair (bp) multiple alignment was edited by hand to minimize the number of unique gaps and to ensure the integrity of the reading frame (available online as Figure S1).
Furthermore, from the estimated size frequencies of the unique gaps, it infers the parameters of the indel size distribution.
For cluster analysis, primer sites, unique gaps, and ambiguously aligned sites were excluded, resulting in a dataset of ≈1,560 aligned sites.
In addition to their level of readiness, behavioral guidance is based on TTM constructs (including decisional balance and self-efficacy), addresses their unique gaps in knowledge, and discusses information relevant to any personal challenges patients could be facing to derail them from transplantation.
In contrast, archaeal H2 producers have a unique enzyme, GAP oxidoreductase (GAPOR), which oxidizes GAP generating one Fdred but no ATP.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com