Your English writing platform
Discover LudwigExact(17)
The second screen entails determining whether the analytes provide unique flux values or multiple flux solutions.
Maximum reduction is obtained for strict coupling, i.e. unique flux relationships.
However, if the system is underdetermined, no unique flux distribution can be calculated.
Similar, 216 alternative distributions with 56.96% unique flux solutions were found for the substrate combination with lowest calculated efficiency.
By applying MFA with a variance-weighted least squares estimation [ 57], we can calculate a unique flux distribution.
Using an iteration of linear programs, unique flux solutions are found in the available flux space for each organism.
Similar(43)
Since flux distributions calculated by FBA are non-unique, flux variability analysis (see Methods) can be used to calculate the span of each flux while still achieving the maximum value for the objective function.
Furthermore, as mentioned above, even for the EMCoA pathway we could not determine a unique RubisCO flux and discussed instead the minimal possible flux (which is zero) whereas the maximal rate is non-zero.
We fix some experimentally determined exchange fluxes, and use geometric FBA [ 57] to choose a unique reference flux distribution consistent with the experimental data.
A unique reference flux (see additional file 2) is chosen from the space of all solutions to the above problem, by finding the box that defines the maximum and minimum values attainable by each v j, then choosing a flux as close as possible to the centre of the box.
For example, in South Africa moderately invasive populations were found in both summer (monsoonal) and winter (polar front) rainfall areas that pose unique nitrogen fluxes, whilst highly aggressive Hawaiian populations inhabit volcanic ash soils that are typically poor in nitrogen.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com