With increasing age, the brain, with its almost unique lymphatic drainage system, develops problems with lymphatic drainage of Aβ and other amyloids and these problems are rarely seen in other organs.
For example, injection of 90 nm virus-like particles via multiple different injection routes (e.g., subcutaneous, intraperitoneal, intramuscular, and intradermal) resulted in unique particle drainage patterns to the inguinal, lumbar, popliteal, and sciatic LNs (36).
Three other haplotypes appear unique to separate drainages: haplotype 25 in Lake Winnipeg and the Upper Mississippi River (A, D E), haplotype 19 from the Ohio/New Rivers (W X), and haplotype 20 in the North River (Y).
This study takes advantage of the unique characteristic of the drainage profiles in the study region, a spatial separation between areas of deep incision east and west of a prominent knickzone, to evaluate three end member scenarios of landscape evolution that could explain the base level fall event(s).
It is clear that alpine populations are subdivided north to south, with unique lineages occupying major drainage basins.
This park was established in 1939 to protect Helmcken Falls and the unique features of the Clearwater River drainage basin, including this volcanic field.
This in vivo approach to image lymphatic drainage provides a unique opportunity to further assess lymphatic drainage of CSF in mouse models of CNS disorders.
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Likewise, yellow perch from the Gulf Coastal drainage possessed high endemism, unique haplotypes, and extensive divergence [ 67].
